Uncertainty, Complexity and Constraints: How Do We Robustly Assess Biological Responses under a Rapidly Changing Climate?

Look-back notification: how do we assess effectiveness?

LA PRATIQUE QUI CONSISTE À PROCURER AUX RECEVEURS DE TRANSFUSION de nouveaux renseignements sur les risques découlant des transfusions qu’ils ont reçues il y a de nombreuses années suscite toujours la controverse. Dans ce numéro (page 149), Nancy Heddle et ses collaborateurs décrivent un programme d’identification rétrospective des patients pédiatriques qu’une transfusion a pu exposer au VIH ou...

A stochastic model for operating room planning under uncertainty and equipment capacity constraints

In the present economic context, the operating theater is considered as a critical activity in health care management. This paper describes a model for operating room (OR) planning under constraint of a unique equipment. At first level we schedule elective surgeries under the uncertainty of using a unique equipment. At the second level we consider emergency surgeries, and at the third le...

Changing the Way We Assess Leadership

Defense leaders face unprecedented challenges of accelerating change in a world without a Cold War. The technology explosion is forcing reduced cycle times as acquisition leaders lead the way to “better, faster, and cheaper.” Specific initiatives and reforms such as single process initiative, electrical combat/electronic data interchange (EC/EDI), cost as an independent variable, and increased ...

Capital Structure under Changing Uncertainty

We explain the puzzle of falling firm leverage during the period of decreasing aggregate volatility from 1970 – 2010 with a simultaneous increase in firm level volatility and varying degrees of firm access to public debt markets. By incorporating friction between public and private debt, a structural model where firms make financing policy decisions in presence of uncertainty can explain a sign...

Do We Know What We Do not Know? A Response to Celine Bonnet